Questions tagged [population-attributable-fraction]

The proportion of cases in the entire population attributable to the exposure of interest.

The population attributable fraction (PAF) is an important epidemiological concept, allowing the estimation of how many cases of a disease in the whole population are due to an exposure in a subset of the population.

A basic treatment of the subject is available here.

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How much lung cancer is really caused by smoking?

On tobacco products one can often see the statistic that nine out of ten lung cancers are caused by smoking but is this number accurate? I am sceptical about this stat for two reasons. Firstly, if you compare cigarette consumption rates over time…
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Population Attributable Fraction adjusted for a variable

I am working in R tryign to estimate the population attributable fraction (PAF) for a binary outcome and 2 exposure variables that I had to coerce to become binary. I have used the "epi.2by2" function within epiR, but that gives me the simple…
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Fractional regression in r / stata

Does anyone know how to predict with the model fracreg ( fractional logit regression) in R or stata? the normal predict function didnt do the job
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Whats the difference between logistic regression and fractional response model?

Can anyone tell me the theory behind fractional response model, how it really works? I wonder if the logistic regression works only with binary variable {0,1}, why when conducting a GLM with quasibinomial family on fractional variable [0-1], it…
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Confidence interval for Population Attributable Fraction with several strata

I have used aggregated data to create a table of person-years (pys) and deaths by social class, age and sex. If we consider social class to be a modifiable factor, we can calculate the number of 'expected' deaths in a situation where the low class…
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How to calculate proportion of the population

I am trying to calculate population attributable fraction. The formula that i am using is $$ \frac{P_e(RR-1)}{P_e(RR-1) + 1} $$ I am using this website as guide:…
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Attributable Risk vs Absolute Risk Reduction

I am hoping to understand the difference between attributable risk and absolute risk reduction. Mathematically, the two entities seem equivalent, but the formulas for calculating their confidence interval are quite different…
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Attirbutable risk from competing risks

There are a number of ways to estimate attributable risk fractions from Cox regression and logistic regression. Does anyone know how to estimate attributable risk from a competing risks regression using subdistribution hazard ratios, with 95%…
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How to calculate whether a disease outcome in a population is by chance or significant?

I have a huge dataset of longitudinal medical records. Each record contains indications for drug and disease. I have been able to calculate the Outcome Rate in the population given a particular drug. This is, simply 1 minus the ratio number of…