Questions tagged [drug]

5 questions
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Most appropriate calculation of mean and standard deviation for drug compliance?

I have 102 patients that were expected to receive 8601 doses of a drug in total. In reality, they received 7992 doses. I understand this to be an overall compliance of 92.9% in this group. Is this an appropriate measure of "mean" compliance? I have…
jserv
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Study the effect of 2 drugs on a symptom caused by 2 diseases

A symptom (for e.g. Headache) can be caused by 2 different diseases (X and Y). Drug “A” acts on both diseases (X and Y). Drug B acts on only second (Y) disease. Disease “X” patients will be treated with drug “A” ONLY. I want to analyse the effect of…
DrWho
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How to study the effect of 2 drugs (used singly and in combination) compared to a placebo on a disease

I want to study the effect of 2 drugs (used singly and in combination) compared to a placebo on a disease. What is the best statistical method? Kindly provide full details.
DrWho
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Percentage change

I have paired data pre and post-exposure to a drug. I would like to calculate the percentage change of my metric in response to the drug. I am getting a little confused and I am probably overthinking it. I think I should calculate the change per…
Jaffie
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How to calculate whether a disease outcome in a population is by chance or significant?

I have a huge dataset of longitudinal medical records. Each record contains indications for drug and disease. I have been able to calculate the Outcome Rate in the population given a particular drug. This is, simply 1 minus the ratio number of…