Questions tagged [absolute-risk]

Absolute risk, is a synonym for incidence. This is a "measure of the rate at which people without a disease develop it during a specific period of time"

Source: Everitt, Cambridge Dictionary of Statistics, Cambridge University Press, 1998.

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How do you explain the difference between relative risk and absolute risk?

The other day I had a consultation with an epidemiologist. She is an MD with a public health degree in epidemiology and has a lot of statistical savvy. She mentors her research fellows and residents and helps them with statistical issues. She…
Michael R. Chernick
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Proof that posterior median is the Bayes estimate of absolute loss?

It is always argued that the posterior median is the Bayes estimate associated to the absolute loss function. The proofs I have come across rely on differentiating the conditional Bayesian risk and equating this to zero. However, this shows that…
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How are absolute risks estimated by the Cox model?

According to my modest understanding, the Cox model is all about estimating hazard ratios, relative measures of risk. However, it is possible (in R using e.g. the packages pec or peperr) to estimate absolute risks by a Cox model. How is this done…
miura
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Absolute vs. Relative Difference in Survival Time - Is this possible?

So there's a fairly well characterized difference between relative risk and absolute risk for conventional cohort studies, and for many questions, the absolute risk is arguably more appropriate. Is there an analogous way to measure absolute…
Fomite
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How to convert relative risk into absolute risk

How can I convert relative risk into absolute risk? How can I estimate absolute risk for an individual from the available sources of RR and OR?
user43446
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Tuning a model for predictive performance in a narrow probability range

Assume we model the probability of disease incidence. When an individual's predicted probability of incident disease, or absolute risk, is greater than a certain threshold, we start preventive measures. Therefore, model calibration is most important…
miura
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In suvival analysis, How to derive risk score from hazard function (or survival function)?

I am learning the random survival forest model which output is cumulative hazard function. In the paper[1], they used the interval of cumulative hazard function as risk score. I simulated on Weibull distribution. Let X and Y are the random variable…
Dabiao
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Risk difference with patient-years incidence rates

I am aware that you can compute risk differences as the difference of risk between two treatment arms $( (\text{No. events}_1/ N_1) - (\text{No. events}_2 / N_2))$. However, can I estimate the same using patient-years incidence rather than just…
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Summary RR to % risk increase?

In a comprehensive meta-analysis the 'summary RR per 120 g/day increase in red meat intake was 1.20 (95% CI 1.04–1.38)' In a review citing this information, they have written rather 'a 20% increase in risk of diabetes per 120-g/d increase in red…
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Filtering out noise/insignificant data when testing millions of contingency tables for association

I have a large dataset of around 20 million 2x2 contingency tables, as below: Y=1 Y=0 E=1 a b E=0 c d I want to measure the effect that exposure (E) has on the expression of a trait (Y). The trait under test is always unique for…
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Cox proportional hazards: converting the linear predictor to absolute risk

I'm doing survival analysis with a data set of 200 patients. They each have 5 continuous biomarker variables, a time variable and a yes/no event variable. I fit a Cox proportional hazards model with the 5 biomarker variables and I'm using the…
Scarper
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Can I just add up the lifetime risk of colon cancer and of rectal cancer to obtain a lifetime risk of colorectal cancer?

I have data from the Dutch Cancer Registry in which they calculated the lifetime risk of colon cancer and rectal cancer separately. I wish to use the data for colorectal cancer as a whole. Can I just add up these numbers? If not, what is the…
Ceailloig
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How can I estimate the risk difference confidence interval with the standard errors of the risks?

I have two risks estimated from imputed data, so I cannot say I have a1 events in the exposed and a0 events in the unexposed, as each data set is different. The output of the function are risks and standard errors. How do I find the confidence…
Alex
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Attributable Risk vs Absolute Risk Reduction

I am hoping to understand the difference between attributable risk and absolute risk reduction. Mathematically, the two entities seem equivalent, but the formulas for calculating their confidence interval are quite different…
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What's "the clinically important absolute scale"?

In this article, the authors used the sentence "...risk difference (i.e., treatment effect on the clinically important absolute scale)". What did they mean by "clinically important absolute scale"? Did they mean by "risk difference (RD) (i.e.,…
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