Questions tagged [meta-regression]

A meta-analytic tool that examines the impact of moderator variables on studies' effect size. It is another name for mixed effects model in meta-analysis (moderators are fixed effects, studies are random effects).

From Wikipedia:

Meta-regression examines the impact of moderator variables on study effect size using regression-based techniques. Meta-regression is more effective at this task than are standard meta-analytic techniques. Alternative models include:

  • Simple regression does not allow for within study variation.
  • Fixed-effects regression does not allow for between study variation. If effect sizes have excess heterogeneity, the fixed effects meta-regression model may be most appropriate.
  • Random or mixed effects regression allows for within study variation and between study variation and is therefore the most appropriate model to choose in many applications.

References

- Stanley, T. D., & Doucouliagos, H. (2009). Meta-regression analysis in economics and business. New York: Routledge.
- Stanley, T. D., & Jarrell, S. B. (1989). Meta‐Regression analysis: A quantitative method of literature surveys. Journal of Economic Surveys, 3(2), 161–170.
- Thompson, S. G., & Higgins, J. (2002). How should meta‐regression analyses be undertaken and interpreted? Statistics in medicine, 21(11), 1559–1573. Retrieved from http://rds.epi-ucsf.org/ticr/syllabus/courses/18/2007/05/03/Lecture/readings/Thompson%20-%20Meta-Regression.pdf.

179 questions
20
votes
2 answers

Multiple imputation for outcome variables

I've got a dataset on agricultural trials. My response variable is a response ratio: log(treatment/control). I'm interested in what mediates the difference, so I'm running RE meta-regressions (unweighted, because is seems pretty clear that effect…
12
votes
2 answers

Can I include an effect size as an independent variable in a meta-regression?

My question is whether I can use an effect size $X$ as a dependent variable and another effect size $Y$ as the independent variable in a meta-regression? For example, I conducted a meta-analysis for the effects of exercise in drinking problems and I…
10
votes
2 answers

Alternate weighting schemes for random effects meta-analysis: missing standard deviations

I am working on a random effects meta-analysis covering a number of studies which do not report standard deviations; all studies do report sample size. I do not believe it is possible to approximate or impute the SD missing data. How should a…
Jennifer
  • 333
  • 1
  • 8
10
votes
1 answer

Torn between PET-PEESE and multilevel approaches to meta-analysis: is there a happy medium?

I am currently working on a meta-analysis, for which I need to analyze multiple effect sizes nested within samples. I am partial to Cheung's (2014) three-level meta-analysis approach to meta-analyzing dependent effect sizes, as opposed to some of…
9
votes
2 answers

How to best handle subscores in a meta-analysis?

I am conducting a meta-analysis of effect sizes d in R using the metafor package. d represents differences in memory scores between patients and healthy. However some studies report only subscores of the measure of interest d (e.g. several different…
jokel
  • 2,403
  • 4
  • 32
  • 40
9
votes
1 answer

Multilevel multivariate meta-regression

Background: I'd like to conduct a meta-regression using studies which have (1) several outcomes/constructs (= multivariate) and (2) multiple effect sizes for every of these outcomes because of different measures. Here's a scheme that hopefully…
8
votes
1 answer

Oddly large R squared values in meta regression (metafor)

I am using the metafor package in R. I have fit a random effects model with a continuous predictor as follows SIZE=rma(yi=Ds,sei=SE,data=VPPOOLed,mods=~SIZE) Which yields the output: R^2 (amount of heterogeneity accounted for): …
user21879
  • 217
  • 3
  • 8
7
votes
2 answers

Step-wise Bayesian updating as a prior selection strategy

There is a famous principle in Bayesian that says: 'Yesterday’s posterior is today’s prior'. Lindley (2000). Now, suppose there are three studies conducted chronologically. Based on Lindley's (2000) principle, is it possible to use a wide prior for…
rnorouzian
  • 3,056
  • 2
  • 16
  • 40
7
votes
1 answer

Is stratified meta-analysis more or less objective than meta-regression?

Reviewer asked me why I use meta-regression as a way how to deal with heterogeneity among effect sizes instead of conducting stratified meta-analysis. I tried to google "stratified meta-analysis" and probably the most useful explanation…
6
votes
1 answer

Meta-analysis of prevalence at the country level

I'm working on a meta-analysis of prevalence data. The aim is to get estimates of prevalence at the country level. The main issue is that the disease is highly correlated with age, and the sample ages of included studies are highly heterogeneous.…
J. Riou
  • 61
  • 5
6
votes
2 answers

How to do meta-regression in SPSS?

I am trying to manage a meta-regression in SPSS17 using the effect size as the dependent variable. I want to explore if my independent variables affects the effect size. Some small practical questions: What is the minimum number of studies…
Staty Despair
  • 359
  • 1
  • 4
  • 13
6
votes
1 answer

What is the best way to regress proportions (as both dependent and independent variables)?

I am currently conducting a meta-analysis and have pooled the prevalence of a certain disease. I would like to check for any association of risk factors, such as gender, ethnicity, and disease classification (which I have all input as proportions),…
Aaron Mai
  • 83
  • 4
6
votes
1 answer

Easy post-hoc tests when meta-analyzing with the `metafor` package in r

I am conducting meta-analysis using metafor in R. I would like to compare among 7 levels in a factor (i.e. different types of treatments). fit <- rma (yi, vi, mods = type_of_treatment - 1, data = dat) fit I found several websites explaining how to…
6
votes
1 answer

Difference between Meta-Analysis, Meta-Regression and Moderator-Analysis

What is the difference between the classic meta-analysis (that aggregates effect sizes from a sample of studies to a summary effect size), meta-regression analysis and moderator analysis? As I understood moderator analysis is used to explain…
franz
  • 79
  • 1
  • 3
5
votes
3 answers

Power of Meta Regression

Why it is said that Meta Regression analyses have low power? & How to calculate the same?
1
2 3
11 12