You can't do that exactly, but something very similar. Take the difference of all pairs (actual value minus simulated) and compute a one-sample t-test to test, whether the difference is different from 0. The p-value will not be of any interest to you, as that deals with the question of the difference being exactly $0.0000000000\dots$
However, most statistic programs will not only give you a p-value but also a 95% confidence intervall of the true difference. You may define for yourself, that you consider the sample mean differences as similar, if the 95%-confidence interval does not contain values above 0.5 or below -0.5 or any other limit of practical equality (ok, this may work even better with a Baysian credible interval, but given the question you will need an answer that es easy to produce).
A worked example in R
:
simulated <- c(3.8, 3.2, 4.7, 9.9, 1.2)
measured <- c(3.2, 3.8, 4.8, 10.3, 1.3)
delta <- simulated - measured
print(t.test(delta, mu = 0)$conf.int)
This will give a 95% confidence interval from -0.685
to 0.445
. Now you can decide, whether that is similar enough for your purposes. Other software will be able to achieve the same similarly easy.