Suppose two samples A and B of size N = 20 are taken from a population of pairs $(Y_i, X_i)$, and separate OLS regressions are calculated from each sample for the model: $$Y_i=\beta_1+\beta_2X_i+\varepsilon_i$$
Considering say the slope coefficient, this yields two estimates $\hat\beta_{2A}$ and $\hat\beta_{2B}$ and their associated standard errors $s_{2A}$ and $s_{2B}$. It is possible then to apply a t-test of a null hypothesis that I provisionally state as follows:
$H_0$: The difference between the mean of the sampling distribution of the estimate of $\beta_2$ associated with sample A and the mean of the sampling distribution of the estimate of $\beta_2$ associated with sample B is less than $\Delta$.
Here $\Delta$ is the size of difference that would be of practical concern given the purpose of the model (I've been guided here by the answers to this question).
Since the standard errors are likely to differ, the appropriate test appears to be Welch’s t-test, the test statistic being (assuming $\hat\beta_{2A} > \hat\beta_{2B}$):
$$t=\frac{\hat\beta_{2A}-\hat\beta_{2B}-\Delta}{\sqrt(s_{2A}^2+s_{2B}^2)}$$
I can see how to do the calculation, and see in general terms that if the null hypothesis were to be rejected, that might suggest departures from the assumptions of the classical linear regression model or non-randomness in sample selection. However, I am puzzled as to what exactly is tested by such a t-test.
Question: How could my formulation of $H_0$ be improved to indicate more precisely what this application of a t-test actually tests? As formulated, it sems to assume that it makes sense to refer to the sampling distribution of a particular sample. This seems wrong because a sampling distribution (of a statistic such as the mean) is a property of repeated samples, not of just one sample. If the two samples had been drawn from distinct sub-populations, then it would make sense to refer to the sampling distributions of the means for each sub-population. But this is not the case here: both samples are drawn from the whole population.