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Now we want to create a new test (Method A) to screen for a disease. In fact, there is a ‘gold-standard’ screening test for the disease (Method B). And the test result of gold-standard (Method B) is binary (Positive vs. Negative).

However, the test result of the new test (Method A) is 3-class classification (Positive vs. Negative vs. Doubtful).

Could we still calculate the sensitivity and specificity as being ways to indicate the accuracy of the new test (Method A)? (Table 1) table1

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