3

I have repeated (x4) measurements on 90 subjects. The outcome is zero inflated.

The model output gives these estimates:

Coefficients:
                         Estimate Std. Error z value   Pr(>|z|)  
(Intercept)               -2.2151     1.6998   -1.30    0.193 
time                       0.5283     0.2167    2.44    0.015
X                          0.0791     0.3267    0.24    0.811
time:X                    -0.1525     0.0611   -2.49    0.013
Y                          1.0348     0.4488    2.31    0.021
time:Y                    -0.0037     0.0583   -0.06    0.950

Number of observations: total=342, Subject=90
Random effect variance(s):
Group=Subject
            Variance StdDev
(Intercept)    6.302   2.51
Negative binomial dispersion parameter: 3.9265 (std. err.: 0.69723)
Zero-inflation: 0.13169  (std. err.:  0.027756 )

X and Y both vary at the subject-level only, not at the time-level.

As you see, here the main effect of X is not significant, while the time:X interaction is significant. On the other hand, the main effect of Y is significant, while the time:Y interaction is not.

I believe that in the case of Y, this means that subjects with higher values of Y have higher trajectories of the outcome. Is this correct ?

However, how is the time:X interaction to be interpreted ?

kjetil b halvorsen
  • 63,378
  • 26
  • 142
  • 467
Joe King
  • 3,024
  • 6
  • 32
  • 58
  • 1
    As discussed [here](http://stats.stackexchange.com/questions/4964/is-interaction-possible-between-two-continuous-variables), there are a lot of difficulties and various problems that can arise in interpreting the interaction between two continuous variables. – Randel Aug 27 '13 at 16:01
  • Possible dups: https://stats.stackexchange.com/questions/177337/significant-interaction-but-non-significant-simple-slopes, https://stats.stackexchange.com/questions/4964/is-interaction-possible-between-two-continuous-variables, https://stats.stackexchange.com/questions/62921/how-to-interpret-the-significant-interaction-of-two-non-significant-main-predict – kjetil b halvorsen Oct 08 '19 at 08:36

0 Answers0