I know the F-test determines if two samples are different based upon their variances, whilst the t-test determines if two samples are different based upon their mean (but include the variance, as standard deviation in the formula, unlike the F-ratio).
My research group uses a data mining tool based on calculating the F-ratio. Sections with high F-ratio are ranked highly, and then features are mined based upon the magnitude of the F-ratio. However, my advisor is telling me that the true indication of whether it is possible to discover a feature is if it passes a t-test. In other words, she says that in order for something to be significant in terms of the F-ratio, it must also pass the t-test. I always thought that these two were unrelated tests, and have different applications, and are used independently. Which is true?