The following $n\times n$ determinant identity appears as eq. 19 on Mathworld's entry for the Chebyshev polynomials of the second kind:
$$U_n(x)=\det{A_n(x)}\equiv \begin{vmatrix}2 x& 1 & 0 &\cdots &0\\ 1 & 2x &1 &\cdots &0 \\ 0 & 1 & 2x &\cdots &0\\0 & 0 & 1 & \ddots & \vdots \\ \vdots & \ddots & \ddots &\ddots & 1\\ 0 & 0 & \cdots & 1 & 2x\end{vmatrix}$$
as can be proven (for example) by expanding by minors to get the recurrence relation for $U_n(x)$.
While working on a spectral problem for my research, I noticed that this result can be extended. Suppose we consider the determinant of $A_n(x)+t\,\mathbf{e}_k \mathbf{e}^T_k$ where $t$ is some free parameter and $k$ is some index. Then the $k$-th column vector may be expressed as $$\mathbf{e}_{k-1}+(2x+t)\mathbf{e}_k+\mathbf{e}_{k+1}= (\mathbf{e}_{k-1}+2x\,\mathbf{e}_k+\mathbf{e}_{k+1})+t\,\mathbf{e}_k.$$ Since the determinant is an linear function of its $k$-th column vector, we can expand in two terms: The first is just $\det{A_n(x)}=U_n(x)$, and for the second we can expand by minors to get a block diagonal matrix $\text{diag}(A_{k-1}(x),A_{n-k}(x))$ with determinant simplying to $U_{k-1}(x)U_{n-k}$. Putting these together gives the result $$\det{A_n(x)+t\,\mathbf{e}_k\mathbf{e}^T_k}=U_n(x)+t \, U_{k-1}(x)U_{n-k}(x).$$
One can similarly introduce a second parameter at a different row vector and compute the resulting determinant. Hence there should be a well-defined answer to the following question:
Given a set of $n$ parameters $\{t_k\}$, express $\det{(A_n(x)+\text{diag}(\{t_k\}))}$ in terms of $\{U_n(x)\}.$