Biology Stack Exchange
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Questions tagged [transplantation]

25 questions
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1 answer

What is the rationale behind tapering of immunosuppressant dose a while after transplant?

MMF, Cyclosporine, Prednisolone, Tacrolimus the dose of whatever immunosuppressant used is reduced in around 6 months - 1 year after the transplant. What is the rationale behind this? Wouldn't any allograft, howsoever old, still remain foreign?…
Polisetty
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Is brain transplantation possible?

Many organs can be transplanted nowadays, including the liver, lungs and kidneys. Can the brain be transplanted?
Irvan Santoso
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1 answer

Is DNA replaced after organ donation?

If an organ from person A is transplanted to a new human body B, is it possible that we can detect A's DNA in B? How long until the organ's DNA is replaced by B's DNA so that we are no longer able to detect any signature of A?
questionhang
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Why does organ transplant work although it seems organ's motor neuron isn't connected to recipient's CNS

Although it seems impossible with current technology to connect organ's capillaries to the recipient's capillaries and its motor neuron to the CNS, transplanted organ works for years. But why?
Math.StackExchange
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Is organ transplantation race dependent?

I watched (IMHO canibalistic) movie "Seven Pounds" where protagonist donated many of his organs to other people and I noticed, that most recipients were black also as protagonist was. Is race really taken into account when organ…
Dims
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Is transplantation of neurons between species possible?

Can brain tissue from one species be implanted into the brain of another species? Because the brain is tolerant to the introduction of antigens (it is said to be immuno-privileged), I was wondering whether neurons would be subject to graft…
Mystery
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Anti-antibodies for preventing transplant rejection

Transplanted organs from the donor are attacked by antibodies from the recepient. So can't we construct anti-antibodies and destroy specifically those antibodies which are causing the rejections ? (Instead of giving immuno suppressants) Well, I can…
biogirl
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Retina Transplant Difficulties

Why is retina transplant not as easy as the normal eye donation and transplant (I think the latter involves the cornea ) ? This says that a new method has come up but why isnt the process similar and simple as the normal transplant ? What are the…
Rajesh
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Transplant rejection through direct allogenic antigen detection: where do the T cells come from?

I just read a chapter in Janeway's Immunology on T cell development and thought about transplant rejection. But I couldn't figure out how the t cells develop which lead to the rejection. So in direct allogenic antigen detection antigen-presenting…
taikuri
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Organ and Bone Marrow Transplantation?

In organ transplantation the transplant is rejected by the body's immune system , but is it possible if along with organ transplant if bone marrow transplantation is carried out from the same donor , then will the Cell Mediated immunity still reject…
Chloritone_360
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Which organs can be donated after clinical death?

The information I found about organ donation does not address clinical death. For example: The process of donation takes place only after physicians declare a person brain dead [...] cessation of brain function [...] is irreversible. However,…
Sparkler
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Would a hole in a heart make it unsuitable for transplantation?

Would a hole in a heart instantly make it unsuitable for transplantation? Or could it be possible for a heart with a congenital defect to still be suitable for use is someone else's body?
Summer
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Corneal transplant and HLA matching

Is HLA matching/ blood grouping required for corneal transplants ? I think,it shouldn't be, because cornea is avascular. I tried searching on the net but most of the references are old and controversial. So please provide a reliable and latest…
biogirl
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Why will tissue from identical twin be rejected in some cases?

Also, transplants from one identical twin to another are almost never rejected. [ Source: Medline Plus ] Why can a tissue from an identical twin be rejected ?
biogirl
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How do transplanted stem cells find their way to bone marrow?

Miraculously, transplanted stem cells find their way to the bone marrow missing the stem cells. How do they achieve this?
hello all
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