Dendritic spines are microscopic protrusions emanating from dendrites of neurons. They serve as post-synaptic targets for pre-synaptic axonal boutons.
Questions tagged [dendritic-spines]
3 questions
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3 answers
Under what conditions do dendritic spines form?
I'm looking for resources or any information about the formation of dendritic spines and synaptogenesis, especially in relation to how new connections are formed on a daily basis.
Does the electrotonic signalling along the axons and through the…
deceleratedcaviar
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Scaling of Ca2+/biochemical signals with dendritic spine size?
I am looking for references that discuss the scaling of biochemical signals in dendritic spines with spine size/synaptic strength. A recent paper (Walker et al. 2017) reports attenuation of NMDA receptor Ca2+ signal with increasing spine size,…
Gaurang
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Calcium concentration in activated dendritic spines?
What are the typical calcium levels reached in single postsynaptic spines following activation of NMDA receptors by an EPSP or backpropagating spike? Everyone seems to refer to that one Neuron paper (Sabatini et al. 2002) which reports experimental…
Gaurang
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