Questions tagged [biochemistry]

The study of chemistry within the scope of biology: the compounds that occur and the reactions involving them in living organisms.

Some Basic Definitions:

Biochemistry is the branch of science that explores the chemical processes within and related to living organisms. It is a laboratory-based science that brings together biology and chemistry. By using chemical knowledge and techniques, biochemists can understand and solve biological problems.(1)

Biochemistry is the study of the chemical substances and vital processes occurring in living organisms. Biochemists focus heavily on the role, function, and structure of biomolecules. The study of the chemistry behind biological processes and the synthesis of biologically active molecules are examples of biochemistry.(2)

Brief introduction:

History:

The history of biochemistry can be said to have started with the ancient Greeks who were interested in the composition and processes of life, although biochemistry as a specific scientific discipline has its beginning around the early 19th century. Some argued that the beginning of biochemistry may have been the discovery of the first enzyme, diastase (today called amylase), in 1833 by Anselme Payen, while others considered Eduard Buchner's first demonstration of a complex biochemical process alcoholic fermentation in cell-free extracts to be the birth of biochemistry. Some might also point to the influential work of Justus von Liebig from 1842, Animal chemistry, or, Organic chemistry in its applications to physiology and pathology, which presented a chemical theory of metabolism, or even earlier to the 18th century studies on fermentation and respiration by Antoine Lavoisier.

Main branches:

  • Animal Biochemistry (biochemistry of animals)

  • Plant Biochemistry (biochemistry of plants)

  • Molecular Biology (concerns the molecular basis of biological activity between biomolecules in the various systems of a cell)

  • Cell Biology (study of the different structures and functions of the cell)

  • Metabolism (conversion of food/fuel to energy to run cellular processes, conversion of food/fuel to building blocks for macromolecules, and the elimination of nitrogenous wastes)

  • Immunology (study of immune systems in all organisms)

  • Genetics (study of genes, genetic variation, and heredity in living organisms)

  • Enzymology (study of enzymes i.e. macromolecular biological catalysts)

Applications:

When to use the biochemistry tag?

As defined, this tag should be used for questions regarding chemistry within the scope of biology: the compounds involving/related to cellular metabolism, cellular biology, genetics, biomolecules, enzymes, immune system and the reactions involving them in living organisms.

Links for further information:

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Why is thymine rather than uracil used in DNA?

What is the advantage gained by the substitution of thymine for uracil in DNA? I have read previously that it is due to thymine being "better protected" and therefore more suited to the storage role of DNA, which seems fine in theory, but why does…
Rory M
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Death because of distilled water consumption

One of my friends said that I would die if I drank distilled water (we were using it in a chemistry experiment) I gave it a go and surprisingly did not die. I did a bit of Googling and found this It said that drinking only this kind of water could…
The-Ever-Kid
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Why is the heart not in the middle of the body?

All mammals that I can think of have a high degree of bilateral symmetry (In fact, almost every animal I can think of is like this). So why is the human heart not exactly in the middle of the body? An effect of this is that one lung is slightly…
DrZ214
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Why 20 amino acids instead of 64?

This question got me thinking about amino acids and the ambiguity in the genetic code. With 4 nucleotides in RNA and 3 per codon, there are 64 codons. However, these 64 codons only code for 20 amino acids (or 22 if you include selenocysteine and…
Daniel Standage
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Why are there no organisms with metal body parts, like weapons, bones, and armour? (Or are there?)

Reading this question, Why are there no wheeled animals?, I wondered why no organisms seem to make use of the tensile and other strengths of metal, as we do in metal tools and constructions. I am obviously not talking about the microscopic uses of…
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Human perception of time depending on age

From what I can tell and what thus far all people with whom I discussed this subject confirmed is that time appears to "accelerate" as we age. Digging a little, most explanations I found basically reduced this to two reasons: As we age physically,…
back2dos
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Can scientists create totally synthetic life?

This particular question has been of a great deal of interest to me, especially since it dives at the heart of abiogenesis.
Larian LeQuella
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Why does cutting onions cause tears?​

Why does cutting onions cause tears?​ From a couple of sites, I found that it is because of sulfuric acid produced by onions. But I could not find more details. What is the biochemical pathway by which onions cause tears? Also, which compound is…
superbug
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Why are bruises not lethal?

Given the following: bruises are caused by minor trauma which breaks blood vessels beneath the skin, causing bleeding the mechanism by which bleeding stops is clotting blood clots inside the body have an unfortunate tendency to get into the…
Mason Wheeler
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What does the human body use oxygen for besides the final electron acceptor in the electron transport chain?

My biology teachers never explained why animals need to breathe oxygen, just that we organisms die if we don't get oxygen for too long. Maybe one of them happened to mention that its used to make ATP. Now in my AP Biology class we finally learned…
Gordon Gustafson
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Why do some vegetables taste bitter?

Bitter gourd, cucumber, etc. are bitter to taste. Which chemical causes bitterness in them? I found these when I searched online: this says that it is because of calcium, while this and this talk about physical effects.
user237650
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What does it mean to "write an image and GIF into the DNA of bacteria"?

BBC News recently published an article saying that: An image and short film has been encoded in DNA, using the units of inheritance as a medium for storing information ... The team sequenced the bacterial DNA to retrieve the gif and the image,…
PiratePi
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Ripening bananas artificially: What is the biological theory behind?

I am a resident of the tropical island of Sri Lanka, and we have a strange traditional method to ripen our banana harvest quickly. What we do is this: We dig a pit in earth that is enough to put the whole banana cluster in. Then, after safely laying…
sampathsris
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Why is ATP the preferred choice for energy carriers?

Why is ATP the most prevalent form of chemical energy storage and utilization in most cells?
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Why do animal cells "mistake" rubidium ions for potassium ions?

So, I was browsing the Wikipedia article for rubidium, and came across this interesting tidbit: Rubidium is not a known nutrient for any living organisms. However, rubidium ions have the same charge as potassium ions and are actively taken up and…
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