Biology Stack Exchange
Biology Stack Exchange

Questions tagged [allele]

Alleles are different forms (among many possible alternative forms) of the same gene.

The different eye colors are for example different alleles of the genes that make the eye color.

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Do some genes follow Rock-Paper-Scissors model of dominance?

Assuming there are at least 3 alleles of the gene $G$ in total - $G_R$, $G_S$ and $G_P$ - is there any gene for which the following is true? $G_R$ is more dominant than $G_S$. $G_S$ is more dominant than $G_P$. $G_P$ is more dominant than $G_R$.
rus9384
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How does the molecular machinery choose where to cut a chromosome for recombination?

I'm wondering about a few technicalities of crossover in meiosis. The point of crossover is to create new chromosomes that don't have the same allele combinations as the original two chromosomes. Usually, the chromosomes are cut at the same place on…
Pertinax
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Can a blood type O be born from AB and A parents?

I have a basic understanding of genetics, and I'm really puzzled by this. My grandma's blood type is A (I don't know if it's heterozygous or homozygous) and my grandpa is AB. Yet my mother is type O. Grandma says that my mom is 100% my grandpa's…
Pate Ardealul
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Can sexual reproduction create new genetic information?

Is there a small chance that in sexual reproduction a new allele forms in the off-spring that was not present in either of the parents, or are the alleles in the offspring always from at least one of the parents? Is new genetic information ever…
Kenshin
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Are alleles equally sized?

If alleles occur at the same locus on a chromosome, does that mean they are of the same size? I was under the impression that they were, but I saw a gel electrophoresis testing different alleles of the same gene and saw them separate. I don’t…
lightweaver
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Is there a practical upper limit to ploidy?

In my AP Biology class, we were discussing polyploidy, specifically, its deleterious nature in mammals and its prevalence in plants. We also learned that commercial crops, especially fruit, are often selectively bred for high magnitudes of ploidy.…
Gnumbertester
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How allele is related to trait that is more complex than two cases (ex. height)?

Recently I started to learn about evolution and genetics. Simple stuff at the beginning - some videos, some reading. So far, everything seems to be pretty simple and straightforward. I easily grasp the concept of gene, allele and trait as the basic…
waste
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Microsatellite shifts (peak calling) GeneMapper! Thesis help!

I'm a masters student attempting to conduct a parentage analysis on a population of fish for my thesis. My advisor and post-docs haven't been very helpful, so I need some help! I have dinucleotide microsatellite markers that I've run on a set of…
Sarah
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Ancestral Allele explanation

I'm having some trouble understanding the concept of ancestral allele. What exactly does it mean? What does it have to do with Identity by descent/state? What does it have to do(if anything) with SNP's? Also, how is the concept useful in…
user6417
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Mitotic crossover happens in G1?

I was reading this article in wikipedia and came across this : It has been suggested that recombination takes place during G1, when the DNA is in its 2-strand phase, and replicated during DNA synthesis. If For example - allele A is present on 1…
biogirl
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ABO allele frequencies: Why use the EM algorithm?

In textbooks and lecture notes and slides posted online, determining allele frequencies using blood type information (ABO), under the assumption of Hardy-Weinberg equilibrium, is accomplished using the EM algorithm. It seems to me, though, that this…
fmg
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How does allele dominance work in polyploid organisms?

You know how there are tables to demonstrate allele dominance in diploids, such as the table found in this question? Well, I was wondering how this works with tetraploids, hexaploids, octoploids, etc. One might assume that you would need a…
Brōtsyorfuzthrāx
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Minor Allele Frequency (MAF) higher than 0.5?

I have a set of data in PLINK format (*.bed, *.bim and *.fam files). There are around 2000 individuals in my dataset. I used PLINK to calculate allele frequencies in the population: p-link --bfile data --freq However, in the produced results file,…
IcedCoffee
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Genotype vs Alleles - What's the difference?

I have searched through various websites, however, I am still rather confused with the difference between 'genotype' and 'alleles' since each site seems to be contradicting another site. I would be much grateful if someone could please give me a…
qwerty
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How does sexual reproduction generate more genetic variation?

I'm curious as to why sexual reproduction generates genetic variation. For me, the term genetic variation is a little ambiguous. The way I understand it, it's the number of alleles at a locus in a population or "group" of organisms. But sexual…
DeepLearner
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